Example: TEN4-Facesp Study

Validation of a Clinical Decision Rule to Predict Abuse in Young Children Based on Bruising Characteristics

Mary Clyde Pierce, MD^1,2; Kim Kaczor, MS¹; Douglas J. Lorenz, PhD³; et al

States:  “To optimize the sensitivity of the refined rule, we defined the cost of a false-negative prediction as 20:1 relative to a false-positive prediction.”
This is to assume the harm of missing a true case often far outweighs the inconvenience of over-calling a negative one.

JAMANETWORK LINK TO STUDY

More Info: https://www.youtube.com/watch?v=evFiNHfFJ4o